We are currently engaged in optimization of culture conditions of human bone marrow derived mesenchymal (stromal) stem cells for their expansion and differentiation into cartilage forming cells for the future repair of cartilage defects occurring in osteoarthritis and rheumatoid arthritis. A proprietary system is being explored for the delivery of these cells to the precise location of defects. The research is aimed also to demonstrate (via collaborative efforts with another institution) the lack of any cancer promoting ability in these cultured cells.
We intend to optimize the expansion of marrow-derived mesenchymal (stromal) stem cells and to demonstrate their immune modulatory properties to allow future cellular therapy for Inflammatory Bowel Diseases: Ulcerative Colitis and Crohn’s Disease. Once this goal is reached, research could expand to other immune-related diseases.
So far, all research has been funded from internal sources. In the near future, we are interested in private equity funding. In addition, applications for government small business grants are being considered.